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Sundeep Kumar, H. K.
- Diuretic and Laxative Activity of Ethanolic Extract of Mollugo Pentaphylla Linn
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Authors
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1 School of Pharmaceutical Science & Research, Berhampur University, Berhampur, Odisha -760007, IN
2 School of Pharmaceutical Sciences, SOA University, Bhubaneswar, Odisha-754030, IN
1 School of Pharmaceutical Science & Research, Berhampur University, Berhampur, Odisha -760007, IN
2 School of Pharmaceutical Sciences, SOA University, Bhubaneswar, Odisha-754030, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 4, No 5 (2012), Pagination: 278-280Abstract
Crude ethanolic extract of Mollugo pentaphylla Linn. (family - Aizoaceae) was investigated for diuretic and laxative activity in albino rats at 200 and 400 mg/kg p.o. Which was compared with standard drugs Furosemide (10mg/kg, p.o.) and Agar agar (300mg/kg, p.o.) respectively. The extract was found to produce significant diuretic as well as laxative activity at dose 400 mg/kg. The plant was also found to possess the phytoconstituents like carbohydrates, alkaloids, gums, saponins, flavanoids, tanins and steroids.Keywords
Mollugo Pentaphylla, Acute Toxicity Study, Diuretic Activity, Laxative Activity.
References
- Kiritikar KR and Basu BD. Indian medicinal plants, vol.II, 2nd edn. Lalit Mohan Basu: Dehradun, India, 1993: 1185.
- Anonymous. The wealth of India, Vol.VI. CSIR Publishers: New Delhi, 1999: 397.
- Chopra RN and Chopra IC. Glossary of Indian Medicinal Plants, CSIR Publication, New Delhi, 1956: 121.
- Singh VP, Sharma SK and Khare VS. Medicinal plants from Ujjain district Madhya Pradesh Part II, Indian Drugs Pharm Ind. 5; 1980: 7-12.
- Lin CC, Kan WS. Medicinal plants used for the treatment of hepatitis in Taiwan. Am. J. Chin. Med. 18 (1/2); 1990: 35-39.
- Rajasekaran M, Nair AGR, Gellstrom WJG and Sikka SC. Spermicidal activity of an antifumgal saponin Mollugogenol A obtained from the tropical herb Mollugo pentaphylla Linn. Contraception, 47; 1993: 401-412.
- Jagatheesh K, Sanofer BJ, Elangovan N and Pavan PK. Photochemical, antimicrobial, anti-inflammatory, anticancer and hepatoproductive evaluation of Mollugo pentaphylla linn. Int. J. Curr Trends Sci Tech. 2 (1); 201: 32-40.
- Mukherjee PK. Quality control herbal drugs. Business Horizons Pharmaceutical Publishers, 1st edn., New Delhi. 246-379: 2002.
- Harborne JB. Phytochemical Methods: A Guide to modern techniques of plant analysis. Chapman and Hall, New York. 37- 214: 1984.
- Lipschitz WL, Haddin Z and Kerpscar A. A Bioassay of Diuretics. J. Pharmacol. Exp. 79; 1943: 97-110.
- Adebayo MA, Adebayo JO and Ajaiyeoba EO. Preliminary phytochemical investigation and diuretics studies of Alstonia boonei stem bark in male wistar rats. J. Nat. Rem. 4 (2); 2004: 179-182.
- Jeffery GH, Bassell J, Mendham J and Denny RC, Vogel's Text Book of Quantitative Chemical Analysis, Addison Wesley Longman Ltd., England. 1989: 801.
- Beckette AH and Stenlake JB, Practical Pharmaceutical Chemistry-I, CBS Publishers and Distributors, New Delhi. 1997: 197.
- Bose A, Mondal S, Gupta JK, Dash GK, Ghosh T and Si S. Studies on Diuretic and Laxative activity of ethanolic extract and its fractions of Cleome rutidosperma aerial parts. Phcog. Mag. 2 (7); 2006: 178-182.
- Hoeland RD and Mycek MJ, Lippincott's Illustrated Reviews: Pharmacology, Lippincott Williams and Wilkins, Philadelphia. 2000: 157-158 and 240-241.
- Chodera A, Dabrowska K, Sloderbach A, Skrzypczak L and Budzianowski J. Effect of flavonoid fractions of Solidago virgaurea L on diuresis and levels of electrolytes. Acta. Pol. Pharm. 48; 1991: 35-37.
- Rizvi SH, Shoeb A, Kapil RS and Satya P. Popli.Two diuretic triterpenoids from Antidesma menasu. Phytochemistry. 19 (11); 1980: 2409-2410.